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Immunotoxicology

Immunotoxicology is the study of immune system dysfunction that can occur as a result of occupational, accidental, or therapeutic exposure to a variety of chemical or biologic agents that affect human health and modify the immune system. Immunotoxicology can appear in a variety of ways, with immunosuppression being one of the most common. Immunotoxicology studies how medications and substances in the environment affect the immune system. Immune systems linked to a wide range of toxins are investigated. Immunotoxicologists study the immune-mediated effects of a variety of xenobiotics, including as pharmaceuticals, environmental pollutants, chemicals, and physical agents (i.e., UV light, radiation). In both experimental animal models and human investigations, efforts have been undertaken to investigate the links between laboratory markers of immune response and disease resistance. Immunotoxicology is primarily concerned with the identification of sensitive endpoints and the creation of experimental procedures to detect suspected immunotoxicants.

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