Oral Presentation (Virtual)
Naylya Djumaeva, Research Institute of Virology, Uzbekistan
Background: Prednisolone and methotrexate are established immunomodulatory agents, but methotrexate is conventionally used at weekly doses substantially higher than those described here. Long-term clinical observations prompted exploration of substantially reduced doses in s [....] » Read More
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through biodesign inspired and immunology related translational applications to secure human healthcare and biosafety
Sergey Victorovich Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Despite breakthroughs in research that have led to an increased understanding of PPM (Personalized & Precision Medicine) based human disease, the translation of discoveries into the areas of diagnostic tools and targeted medicines has not kept pace with medical need. It [....] » Read More
Title : Antibody proteases as translational biomarkers, targets, and biocatalysts of the next generation step as applicable for design driven precision medical practice
Sergey Victorovich Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Biomarkers as being a part of the ligand-receptor tandems have induced an impulse to prompt the development of an upgraded concept of the targeted therapy. So, the identification, impact and im-plementation of diagnostic, predictive and prognostic biomarkers of the next step gene [....] » Read More
Title : Targeting tumor-associated antigens through variable epitope libraries: Antitumor activity in breast cancer and acute myeloid leukemia
Braulio Alejandro Martinez Zarco, UNAM, Mexico
Background: Tumor-associated antigens (TAAs) represent attractive targets for cancer immunotherapy; however, tumor heterogeneity and immune escape remain major challenges for antigen-specific vaccination. Variable Epitope Libraries (VELs) are highly diverse collections of mutated [....] » Read More
Title : Treatment outcomes of adult Filipino patients with drug susceptible pulmonary and extrapulmonary tuberculosis after anti-Koch’s rechallenge regimen
Jizelle Kay Cofulan Fang Asan, Baguio General Hospital and Medical Center, Philippines
Introduction: Tuberculosis (TB) remains a significant global health threat, affecting approximately 10 million individuals annually, with 1.5 million deaths, making it the leading infectious killer worldwide. Despite the curability of TB, data on the clinical outcomes of patients [....] » Read More
Title : Clinical, immunological, and cytokine profiles of primary Sjögren’s syndrome in a Western Algerian population
Ouikhlef Narjesse, EHU Oran & Faculty of Medicine of Oran, Algeria
Background: Primary Sjögren’s syndrome (pSS) is a complex systemic autoimmune disease characterized by significant clinical and biological heterogeneity, driven by intricate genetic and immunological factors. Data regarding North African pSS cohorts remain scarce. This [....] » Read More
Title : Contribution of anti-phosphatidylserine antibodies in the diagnosis of antiphospholipid syndrome
Abdiche Yasmine, Pasteur Institute of Algeria, Algeria
Antiphospholipid syndrome is an autoimmune disease characterized by vascular thrombosis, obstetric complications, and the presence of antiphospholipid antibodies (aPL). However, diagnosis may be particularly challenging in certain patients who are seronegative for conventional an [....] » Read More