Biography:
Naylya Djumaeva, MD, PhD, is an independent clinician-researcher from Uzbekistan working in scientific collaboration with the Research Institute of Virology, Ministry of Health. She has more than 40 years of clinical and research experience, with longstanding interests in chronic viral infections, immune-mediated disease, neuroimmune interactions, and post-infectious syndromes. Her recent research has focused on low-dose immunomodulatory approaches using prednisolone and ultra-low-dose weekly methotrexate in selected chronic disorders. This work includes published clinical observations in Rett syndrome with epilepsy and childhood-onset Takayasu arteritis, representing distinct neurological and systemic inflammatory disease contexts. Dr Djumaeva also investigates Long COVID and virus-associated regulatory dysfunction, including exploratory electroacupuncture-based medicament testing as an investigational method. Her broader scientific interest is directed toward mechanisms of immune regulation, chronic inflammation, and the potential clinical effects of substantially reduced immunomodulatory drug doses. She has presented her work at national and international scientific meetings and continues to develop interdisciplinary approaches linking clinical observation with hypothesis-driven research.

Title : Ultra-low-dose methotrexate combined with low-dose prednisolone in two distinct chronic disorders: A hypothesis-generating clinical comparison